Vascular
Restless Leg Syndrome
A condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation.
Restless leg syndrome (RLS) is a neurological and vascular condition causing an uncomfortable, irresistible urge to move the legs — typically worse at night or at rest. In many patients, underlying venous insufficiency is a contributing or treatable cause.
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Restless leg syndrome (RLS) frequently disrupts sleep due to irresistible urges to move the legs, often linked to underlying venous issues.
Symptoms
- Uncomfortable sensations in the legs: crawling, tingling, aching, or burning
- Strong urge to move the legs, especially at rest or during sleep
- Symptoms worse in the evening and at night
- Temporary relief with movement
- Sleep disturbance and daytime fatigue
Causes & Risk Factors
- Underlying venous insufficiency or varicose veins
- Iron deficiency and anaemia
- Peripheral neuropathy
- Pregnancy
- Kidney disease
- Certain medications (antihistamines, antidepressants, antinausea drugs)
Diagnosis
- Clinical assessment with detailed symptom history
- Venous duplex ultrasound to assess for underlying venous disease
- Blood tests: iron studies, ferritin, kidney function
- Nerve conduction studies if neuropathy is suspected
Treatment Options
- Treatment of underlying venous disease (ablation or sclerotherapy) when applicable
- Iron supplementation for iron deficiency
- Lifestyle measures: regular exercise, reduced caffeine and alcohol
- Medications: dopamine agonists, gabapentin, pregabalin for moderate to severe cases
Concerned About Restless Leg Syndrome?
Dr. Peter Chang offers specialist assessment and personalised management at Paragon Medical Centre, Singapore.