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VascularInterventional

DVT Mechanical Thrombectomy

A specialized catheter procedure that physically extracts blood clots from deep veins, rapidly restoring blood flow and preventing long-term damage.

Mechanical thrombectomy is a catheter-based procedure that physically removes acute DVT clot from the iliofemoral veins — restoring venous patency rapidly and reducing the risk of long-term post-thrombotic syndrome compared to anticoagulation alone.

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Mechanical thrombectomy device removing a blood clot from a deep vein

Catheter-based mechanical extraction effectively removes fresh thrombus from the deep veins, rapidly restoring normal venous flow.

When It Is Indicated

  • Acute iliofemoral DVT with clot less than 14 days old
  • Severe symptoms: significant limb swelling, pain, and functional impairment
  • Phlegmasia cerulea dolens — a vascular emergency with threatened limb viability
  • Reducing risk of post-thrombotic syndrome in young, active patients

The Procedure

Under fluoroscopic guidance, a venogram confirms clot extent. The ClotTriever or similar mechanical device extracts thrombus from the iliac and femoral veins. May-Thurner syndrome (iliac vein compression) is identified and treated with iliac vein stenting if present. The procedure typically takes 1–2 hours.

Mechanical vs. Thrombolytic Approaches

  • Catheter-directed thrombolysis (CDT) — delivers clot-dissolving medication directly into the thrombus over 12–24 hours
  • Pharmacomechanical CDT (PCDT) — combines catheter-directed thrombolysis with mechanical fragmentation
  • Single-session mechanical thrombectomy — avoids thrombolytic drug use, reducing bleeding risk

Results & Evidence

The CLOUT Registry demonstrates greater than 90% thrombus removal with mechanical thrombectomy, with rapid symptom relief and low major complication rates. Post-thrombotic syndrome develops in up to 40% of patients managed with anticoagulation alone — early clot removal significantly reduces this burden.

After the Procedure

  • Anticoagulation continued for a minimum of 3–6 months
  • Compression stockings worn for at least 2 years
  • Thrombophilia screening for unprovoked DVT
  • Follow-up duplex ultrasound to assess venous patency

Considering DVT Mechanical Thrombectomy?

Dr. Peter Chang will assess your suitability and discuss all treatment options during a specialist consultation at Paragon Medical Centre, Singapore.