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Heart

Acute Coronary Syndrome

A medical emergency, including heart attacks, where blood supply to the heart muscle is suddenly blocked.

Acute Coronary Syndrome (ACS) covers STEMI, NSTEMI, and unstable angina — all caused by sudden loss of blood flow to the heart and requiring urgent specialist care. Time-critical intervention is essential to prevent permanent cardiac damage or death.

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Diagram showing acute coronary syndrome with a sudden blockage in a heart artery

Acute coronary syndrome requires immediate medical attention, as a sudden blockage can quickly cause irreversible damage to the heart.

Types of ACS

  • STEMI — complete coronary artery blockage requiring immediate emergency angioplasty
  • NSTEMI — partial arterial occlusion with detectable heart muscle damage, requiring urgent catheterisation within 24–72 hours
  • Unstable Angina — chest pain at rest or with minimal exertion signalling imminent heart attack risk

Symptoms

  • Crushing chest pressure, tightness, or heaviness
  • Pain radiating to the arm, jaw, neck, or back
  • Breathlessness, cold sweats, and nausea
  • Sudden fatigue
  • Atypical presentations in women, older adults, and diabetic patients: back pain, indigestion-like discomfort, or unexplained fatigue

Causes & Risk Factors

  • Atherosclerotic plaque rupture triggering acute blood clot formation
  • Hypertension, hyperlipidemia, diabetes, smoking
  • Obesity, physical inactivity, family history

Diagnosis

  • 12-lead ECG
  • Serial cardiac troponin blood tests
  • Echocardiography
  • Coronary angiography

Treatment Options

  • Primary percutaneous coronary intervention (PCI) with stenting for STEMI
  • Antiplatelet therapy and anticoagulation for NSTEMI and unstable angina
  • Coronary artery bypass surgery (CABG) for complex multi-vessel disease
  • Long-term medications: statins, beta-blockers, ACE inhibitors, dual antiplatelet therapy

Concerned About Acute Coronary Syndrome?

Dr. Peter Chang offers specialist assessment and personalised management at Paragon Medical Centre, Singapore.